I’m Abby L. Manning, a PhD candidate exploring how cells bring the right transcription machinery together—at the right place and time.
Wagner Lab · University of Rochester
Transcription depends on proteins finding one another and working together with remarkable precision. I’m interested in the molecular interactions that recruit and coordinate these proteins across different classes of RNA genes.
In Eric Wagner’s lab, my doctoral research focuses on ICE2 and its connections to the cap-binding complex and Integrator in small nuclear RNA transcription. I combine biochemical and cellular approaches with structure-guided experiments to investigate how these interactions support function.
Saad, Delaforge, Manning, and colleagues
Co-first author
Outside the lab, I enjoy photography, collage, crochet, and imaginative worlds. Making things—and looking closely—is a thread that runs through both my science and my creative life.
Interested in transcription, molecular mechanisms, or connecting across disciplines? I’d love to hear from you.
CV: October 2026 edition · Rochester, New York